Journal of Clinical Medicine Research, ISSN 1918-3003 print, 1918-3011 online, Open Access
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Case Report

Volume 16, Number 9, September 2024, pages 436-439

Physiological Stimulus for the Synthesis of Basement Membrane Proteins Leading to Its Reconstruction

Figure

Figure 1.
Figure 1. Rupture of basement membrane (ruptures/mm), before, and after treatment: epidermis-dermis interface, region of basement membrane - collagen III. (a) Graph of ruptures/mm of epidermis-dermis interface before and after treatment. Note significant difference between groups. (b, d) Region of basement membrane (papillary epidermis-dermis interface) prior to treatment, with reticular fibers (collagen IV) presenting ruptures and discontinuity. (c, e) Region of basement membrane showing return of structural continuity and thickness in regions of previous rupture. Epi: epidermis; arrowhead: rupture of collagen III in region of basement membrane; arrows: continuity and thickness of reticular fibers in region of basement membrane. Staining: Gomori’s reticulin.

Table

Table 1. Morphometry of Epidermis (µm) and Dermal Papillae (µm)
 
BeforeAfter
a, bDifferent letters denote significant difference between groups (P < 0.05).
Rupture of basement membrane (ruptures/mm)1.59 ± 0.11a0.89 ± 0.09b