Journal of Clinical Medicine Research, ISSN 1918-3003 print, 1918-3011 online, Open Access
Article copyright, the authors; Journal compilation copyright, J Clin Med Res and Elmer Press Inc
Journal website https://jocmr.elmerjournals.com

Original Article

Volume 16, Number 11, November 2024, pages 554-563

Construction of a Clinical Prediction Model for Complications After Femoral Head Replacement Surgery

Figures

↓  Figure 1. Nomogram prediction of the risk of complications after femoral head replacement. ALB: serum albumin; AST: aspartate aminotransferase; WBC: white blood cell.
Figure 1.
↓  Figure 2. Internal verification of nomogram-calibration curve.
Figure 2.
↓  Figure 3. ROC curve. ROC: receiver operating characteristic; AUC: area under the curve; CI: confidence interval.
Figure 3.
↓  Figure 4. Decision curve in the model.
Figure 4.

Tables

↓  Table 1. Assignment of Related Indicators
 
Name Variable assignment and description
Complication 0 - no, 1 - yes
Preoperative diagnosis of injury modality 0 - fracture, 1 - caput femoris necrosis
Operation mode 0 - anterior approach,1 - posterior approach
Bone cement 0 - no, 1 - yes
Osteoporosis 0 - no, 1 - yes
Hypertension 0 - no, 1 - yes
Diabetes 0 - no, 1 - yes
Smoking 0 - no, 1 - yes
Drinking 0 - no, 1 - yes

 

↓  Table 2. Baseline Characteristics
 
Variables Total (n = 186) No complications (n = 144) Complications (n = 42) Statistic P
BMI: body mass index.
Age 66.76 ± 16.47 66.03 ± 16.69 69.26 ± 15.63 t = -1.12 0.264
BMI 23.20 ± 2.81 23.30 ± 2.82 22.86 ± 2.77 t = 0.89 0.372
Gender, n (%) χ2 = 0.00 0.964
  Female 88 (47.31%) 68 (47.22%) 20 (47.62%)
  Male 98 (52.69%) 76 (52.78%) 22 (52.38%)

 

↓  Table 3. One-Way Logistic Regression Analysis of Complications After Femoral Head Replacement Surgery
 
Variables β SE Z P OR (95% CI)
ALT: alanine transaminase; AST: aspartate aminotransferase; BMI: body mass index; CI: confidence interval; OR: odds ratio; PLT: platelets; WBC: white blood cell.
Age 0.01 0.01 1.12 0.263 1.01 (0.99 - 1.03)
BMI -0.06 0.06 -0.90 0.371 0.95 (0.84 - 1.07)
Operation time (min) 0.11 0.02 4.62 < 0.001 1.12 (1.07 - 1.18)
ALT 0.04 0.02 2.08 0.038 1.04 (1.01 - 1.09)
AST 0.11 0.03 4.30 < 0.001 1.12 (1.06 - 1.17)
WBC 1.06 0.21 5.13 < 0.001 2.90 (1.93 - 4.35)
PLT -0.01 0.02 -0.35 0.725 0.99 (0.96 - 1.03)
Albumin -0.18 0.05 -3.71 < 0.001 0.84 (0.77 - 0.92)
Age
  Male 1.00 (Reference)
  Female 0.02 0.35 0.05 0.964 1.02 (0.51 - 2.02)
Preoperative diagnosis of injury modality
  0 1.00 (Reference)
  1 -0.03 0.39 -0.07 0.940 0.97 (0.45 - 2.08)
Hypertension
  0 1.00 (Reference)
  1 0.24 0.35 0.68 0.493 1.27 (0.64 - 2.54)
Diabetes
  0 1.00 (Reference)
  1 -0.13 0.50 -0.26 0.791 0.88 (0.33 - 2.32)
Smoking
  0 1.00 (Reference)
  1 -0.14 0.47 -0.31 0.759 0.87 (0.35 - 2.16)
Drinking
  0 1.00 (Reference)
  1 -0.05 0.43 -0.11 0.913 0.95 (0.41 - 2.20)
Operation mode
  0 1.00 (Reference)
  1 -0.32 0.35 -0.91 0.365 0.73 (0.37 - 1.45)
Bone cement
  0 1.00 (Reference)
  1 0.40 0.42 0.94 0.349 1.49 (0.65 - 3.41)
Osteoporosis
  0 1.00 (Reference)
  1 1.51 0.38 4.01 < 0.001 4.54 (2.17 - 9.50)

 

↓  Table 4. Multifactorial Regression of Complications After Femoral Head Replacement
 
Variables β SE Z P OR (95%CI)
AST: aspartate aminotransferase; CI: confidence interval; OR: odds ratio; WBC: white blood cell.
Operation time (min) 0.10 0.03 3.25 0.001 1.10 (1.04 - 1.17)
AST 0.10 0.03 3.03 0.002 1.10 (1.03 - 1.17)
WBC 1.11 0.25 4.46 < 0.001 3.04 (1.87 - 4.95)
Serum albumin -0.18 0.06 -3.16 0.002 0.83 (0.74 - 0.93)
Osteoporosis 1.48 0.52 2.85 0.004 4.39 (1.59 - 12.12)